Coronavirus Disease 2019 Vaccination during Pregnancy

Several vaccines have been developed to combat the coronavirus disease 2019 (COVID-19), including messenger Ribonucleic acid (mRNA, Pfizer-BioNtech, and Moderna) viral vector (AstraZeneca Janssen) types. Unfortunately, reports of COVID-19 exposure during pregnancy are scarce, as breastfeeding were among exclusion criteria in efficacy safety studies major vaccines. The U.S. Centers for Disease Control Prevention recently included a risk factor severe infection, although absolute is low. Previous experience pregnant women with mRNA lacking despite such not using live viruses, being unable cause disease, interacting an individual's DNA, genetic mutations. In addition, previous animals revealed any issues vaccine types female reproduction or fetal development. Vaccine-induced antibody titers equivalent lactating versus non-pregnant women. Given data on increased mortality morbidity associated pregnancy, it may be unethical withhold vaccinations based theoretical lack clinical research this population. Additionally, careful review vaccination recommendations by academic community government through additional tailored situation Korea needed.